Doppel protein and its effects on animal reproduction / 生物工程学报
Chinese Journal of Biotechnology
;
(12): 170-175, 2009.
Article
in Chinese
| WPRIM
| ID: wpr-302840
ABSTRACT
Doppel protein (abbreviation Dpl) is a newly recognized Glycosyl phosphatidyl inositol (GPI) anchored and highly glycosylated protein, which is similar to prion protein (PrP) in the chemical structure. The encoding gene of Dpl named PRND locates at the downstream of the prion protein gene (PRNP). These two proteins are different in physiological functions. The expression of Dpl focuses on testis tissue at the adult, and takes an important role in maintaining sperm integrality, normal fertility, and motion ability. We reviewed the biological characters, physiological functions of Dpl and its effects on male reproduction in order to provide theory guidance for the study on physiological function and male reproduction controlling.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Physiology
/
Reproduction
/
Testis
/
Prions
/
GPI-Linked Proteins
/
Metabolism
Limits:
Animals
/
Humans
/
Male
Language:
Chinese
Journal:
Chinese Journal of Biotechnology
Year:
2009
Type:
Article
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