Application of narrow band imaging endoscopy in early diagnosis of nasopharyngeal carcinoma / 中华耳鼻咽喉头颈外科杂志

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the use of NBI (narrow band imaging) in early the diagnosis of nasopharyngeal carcinoma.</p><p><b>METHODS</b>A total of 55 cases with nasopharyngeal lesions (including 9 cases of nasopharyngeal carcinoma after treatment) were examined and diagnosed by white and NBI endoscopy between October 2011 and March 2012, and their diagnosis efficacies were evaluated based on pathological diagnosis as a gold standard. Chi-square test was used to analyze data.</p><p><b>RESULTS</b>Of 55 cases, 12 cases were pathologically diagnosed as chronic mucosa inflammation and 43 as nasopharyngeal carcinoma including 6 recurrent cases, of 43 cases, 40(93.0%) were diagnosed by NBI endoscopy and 18 (41.9%) by white endoscopy. Of 12 cases with early nasopharyngeal carcinoma (5 for stage I and 7 for stage II) , 5(100.0%) for stage I, and 6(85.7%) for stage II were diagnosed by NBI endoscopy but only 1(14.3%) for stage II by white endoscopy, with a statistically significant difference (χ(2) = 10.000, P = 0.008;χ(2) = 7.143, P = 0.029).</p><p><b>CONCLUSION</b>NBI endoscopy can be used in early diagnosis of nasopharyngeal carcinoma and check after treatment.</p>