Diagnostic value of serum angiopoietin-2 level in pancreatic cancer / 中华肿瘤杂志
Chinese Journal of Oncology
;
(12): 47-49, 2011.
Article
in Chinese
| WPRIM
| ID: wpr-303370
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the diagnostic value of serum angiopoietin-2 (Ang-2) level in pancreatic cancer patients.</p><p><b>METHODS</b>Serum Ang-2 level was measured by enzyme-linked immunosorbent assays (ELISA) in samples from 116 patients with pancreatic cancer, 50 patients with chronic pancreatitis, and 50 normal control subjects.</p><p><b>RESULTS</b>The serum Ang-2 level in patients with pancreatic cancer [(1539.0 ± 449.3) ng/L] was significantly higher than those in patients with pancreatitis [(1044.6 ± 246.1) ng/L, P < 0.01] and normal control subjects [(1075.6 ± 228.2) ng/L, P < 0.01]. There was no significant difference of serum Ang-2 levels between patients with pancreatitis and normal controls. Pancreatic caner patients with lymph node metastasis had a significantly higher serum Ang-2 level [(1890.1 ± 354.9) ng/L] than those without metastasis [(1212.1 ± 224.2) ng/L, P < 0.01]. The area under ROC curve of serum Ang-2 level for diagnosis of pancreatic cancer was 0.819.</p><p><b>CONCLUSION</b>The serum Ang-2 level can be a useful indicator for diagnosis of pancreatic cancer.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pancreatic Neoplasms
/
Pancreatitis
/
Pathology
/
Blood
/
Enzyme-Linked Immunosorbent Assay
/
Retrospective Studies
/
ROC Curve
/
Angiopoietin-2
/
Diagnosis
/
Lymphatic Metastasis
Type of study:
Diagnostic study
/
Observational study
/
Prognostic study
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Chinese Journal of Oncology
Year:
2011
Type:
Article
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