Association between perioperative bleeding post percutaneous coronary intervention and 1 year clinical outcomes in elderly patients / 中华心血管病杂志
Chinese Journal of Cardiology
;
(12): 26-30, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-303773
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the association between perioperative bleeding post percutaneous coronary intervention (PCI) and 1 year adverse cardiovascular events in elderly patients.</p><p><b>METHODS</b>From June 2006 to August 2011, 1 105 elderly ( ≥ 75 years) patients undergoing PCI in Fuwai Hospital were prospectively included. Patients were divided into peri-procedure bleeding group (n = 153) and no bleeding group (n = 952). Cox proportional hazards model was performed to evaluate the independent effect of bleeding on the composite endpoint of death and myocardial infarction.</p><p><b>RESULTS</b>BARC 2 grade bleeding occurred in 9.5% (105/1 105) patients. The rate of BARC ≥ 2 grade bleeding was 11.8% (130/1 105) , and the access site-related bleeding accounted for 62.7% (96/153) of all bleeding. The composite endpoint of 1 year death and myocardial infarction was higher in bleeding group (9.2% (14/153) vs. 4.2% (40/952), P = 0.008) . The 1 year cardiac death was higher in bleeding group (3.9% (6/153) vs. 0.8% (8/952), P = 0.007), but the rate of non-cardiac death was similar between bleeding group and no bleeding group (P = 0.360). Cox proportional hazards model analysis showed that HR of 1 year death and myocardial infarction in BARC ≥ 2 grade bleeding patients was 2.368 (95%CI1.201-4.669, P = 0.013) compared with no bleeding patients.</p><p><b>CONCLUSION</b>Perioperative bleeding post PCI is an independent predictor of 1 year adverse outcomes in elderly patients( ≥ 75 years).</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Prognosis
/
Proportional Hazards Models
/
Risk Factors
/
Treatment Outcome
/
Percutaneous Coronary Intervention
/
Hemorrhage
/
Myocardial Infarction
Type of study:
Etiology study
/
Prognostic study
/
Risk factors
Limits:
Aged
/
Humans
Language:
Chinese
Journal:
Chinese Journal of Cardiology
Year:
2015
Type:
Article
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