Roles of G protein-coupled estrogen receptor in the male reproductive system / 中华男科学杂志
National Journal of Andrology
;
(12): 175-179, 2016.
Article
in Chinese
| WPRIM
| ID: wpr-304730
ABSTRACT
The G protein-coupled estrogen receptor (GPER), also known as G protein-coupled receptor 30 (GPR30), was identified in the recent years as a functional membrane receptor different from the classical nuclear estrogen receptors. This receptor is widely expressed in the cortex, cerebellum, hippocampus, heart, lung, liver, skeletal muscle, and the urogenital system. It is responsible for the mediation of nongenomic effects associated with estrogen and its derivatives, participating in the physiological activities of the body. The present study reviews the molecular structure, subcellular localization, signaling pathways, distribution, and function of GPER in the male reproductive system.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Organ Specificity
/
Physiology
/
Reproduction
/
Molecular Structure
/
Signal Transduction
/
Receptors, Estrogen
/
Chemistry
/
Receptors, G-Protein-Coupled
/
Estrogens
/
Genitalia, Male
Limits:
Humans
/
Male
Language:
Chinese
Journal:
National Journal of Andrology
Year:
2016
Type:
Article
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