A new cytotoxic isocoumarin from endophytic fungus Aspergillus versicolor / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 92-95, 2016.
Article
in Chinese
| WPRIM
| ID: wpr-304889
ABSTRACT
A new isocoumarin, along with five known ones,were isolated from the fermentation products of an endophytic fungus Aspergillus versicolorby using various chromatographic techniques.Their structures were elucidated on the basis of extensivespectroscopic analysis, including 1D-and 2D-NMR techniques. Compound 1 was evaluated for cytotoxicity against five human tumor cell lines. The results showed that 1 exhibited weak cytotoxicityagainst NB4, SHSY5Y and MCF7 cells with IC₅₀ values of 6.8, 4.3,8.8 μmol•L⁻¹, respectively.
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Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Journal of Chinese Materia Medica
Year:
2016
Type:
Article
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