Nonexpressor of pathogenesis-related genes 1 (NPR1): a key node of plant disease resistance signalling network / 生物工程学报
Chinese Journal of Biotechnology
;
(12): 511-515, 2005.
Article
in Chinese
| WPRIM
| ID: wpr-305212
ABSTRACT
The NPRI (nonexpressor of pathogenesis-related genes (1) gene, firstly cloned in Arabidopsis thaliana, is a key gene involved in regulation of plant disease resistance. It plays a pivotal role not only in systemic acquired resistance (SAR) and induced systemic resistance (ISR), but also in basic resistance and resistance (R) gene-dependent resistance. NPR1 monomerization induced by enhanced reducing condition after oxidative burst, and the accumulation of NPR1 monomers in the nuclei, are required and enough for expression of PR (pathogenesis-related) genes and SAR. NPR1 regulates PR gene expression through interaction with TGA transcription factors (TF). As a cross-talk point of a variety of defense signaling pathways, probably through direct or indirect interacting with some WRKY TFs and a NPR1-like protein NPR4, NPR1 is essential in balancing salicylic acid- and jasmonic acid- dependent signal transduction pathways, which is achieved through an unknown mechanism in the cytosol. The possible application of NPR1 in plant protection is also discussed in this review.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pharmacology
/
Plant Diseases
/
Signal Transduction
/
Plants, Genetically Modified
/
Gene Expression Regulation, Plant
/
Salicylic Acid
/
Cyclopentanes
/
Arabidopsis Proteins
/
Oxylipins
/
Genetics
Type of study:
Etiology study
Language:
Chinese
Journal:
Chinese Journal of Biotechnology
Year:
2005
Type:
Article
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