Application of lornoxicam to patient-controlled analgesia in patients undergoing abdominal surgeries / 中国医学科学杂志(英文版)
Chinese Medical Sciences Journal
;
(4): 59-62, 2005.
Article
in English
| WPRIM
| ID: wpr-305458
ABSTRACT
<p><b>OBJECTIVE</b>To assess the efficacy and safety of lornoxicam, one non-steroidal anti-inflammatory drug (NSAID) in patient-controlled analgesia (PCA) in patients undergoing abdominal surgeries.</p><p><b>METHODS</b>Thirty-nine patients scheduled for abdominal surgeries were randomly assigned to different PCA treatment groups using either lornoxicam or fentanyl postoperatively. Pain intensity difference (PID) and sum of pain intensity difference (SPID) were used to assess the analgesic efficacy of both drugs during a 24-hour period.</p><p><b>RESULTS</b>The analgesic efficacy of lornoxicam is 1/66 of fentanyl, which was shown by SPID value of 3.250 and 3.058, respectively (P > 0.05). Lornoxicam caused fewer adverse events than fentanyl (33% vs. 68%, P < 0.05).</p><p><b>CONCLUSION</b>In clinic, we can use lornoxicam to treat postoperative pain effectively and with less adverse reactions compared with fentanyl.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pain, Postoperative
/
Pain Measurement
/
Cholecystectomy
/
Piroxicam
/
Anti-Inflammatory Agents, Non-Steroidal
/
Fentanyl
/
Double-Blind Method
/
Analgesia, Patient-Controlled
/
Laparoscopy
/
Therapeutic Uses
Type of study:
Controlled clinical trial
Limits:
Adolescent
/
Adult
/
Aged
/
Female
/
Humans
/
Male
Language:
English
Journal:
Chinese Medical Sciences Journal
Year:
2005
Type:
Article
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