Etiology of aseptic meningitis prevalent in Xuzhou / 中华实验和临床病毒学杂志
Chinese Journal of Experimental and Clinical Virology
;
(6): 66-69, 2006.
Article
in Chinese
| WPRIM
| ID: wpr-305543
ABSTRACT
<p><b>BACKGROUND</b>To find the pathogenic agents of aseptic meningitis prevalent in Xuzhou of Jiangsu province in 2001.</p><p><b>METHODS</b>The enterovirus (EV) was cultured from CSF of the patients and identified with anti-serum by neutralization test. Neutralization titer of antibody in paired sera from meningitis children was determined. EV RNA was detected by RT-PCR.</p><p><b>RESULTS</b>Four strains of Coxsackievirus B5, 2 strains of Coxsackievirus B3 and 1 strain of Echovirus 7 were isolated from 22 CSF specimens. The isolation rate of virus was 31.8% (7/22), 21 CSF were tested by RT-PCR, the positive rate of EV RNA was 52.4% (11/21); 57.9% (11/19) of patients paired-sera had over 4 folds antibody rise or became seroconverted.</p><p><b>CONCLUSION</b>Enterovirus was the pathogenic agent of aseptic meningitis prevalent in Xuzhou of Jiangsu province, the main serotype of the virus was Coxsackievirus B5.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Virion
/
Virology
/
RNA, Viral
/
Neutralization Tests
/
Microscopy, Electron
/
Cerebrospinal Fluid
/
China
/
Epidemiology
/
Prevalence
/
Enterovirus
Type of study:
Etiology study
/
Prevalence study
Limits:
Child
/
Child, preschool
/
Humans
/
Infant
Country/Region as subject:
Asia
Language:
Chinese
Journal:
Chinese Journal of Experimental and Clinical Virology
Year:
2006
Type:
Article
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