High ligation of the spermatic vein and sperm DNA fragmentation / 中华男科学杂志
National Journal of Andrology
;
(12): 897-901, 2011.
Article
in Chinese
| WPRIM
| ID: wpr-305768
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the effect of high ligation of the spermatic vein (HLSV) on DNA fragmentation in varicocele (VC) patients.</p><p><b>METHODS</b>Thirty-four VC patients underwent HLSV. Sperm motion indexes and the results of papanicolaou staining and DNA fragmentation detection were analyzed before and 3 months after the operation according to the WHO guidelines.</p><p><b>RESULTS</b>Compared with pre-operation, HLSV achieved a significant increase in the percentage of morphologically normal sperm (P < 0.01), and remarkable decreases in DNA fragmentation, sperm deformity index (SDI) and multiple anomalies index (MAI) (P < 0.01). The patients also showed significant increases in sperm concentration and the percentages of grade b sperm (P < 0.05) and grade a and a + b sperm (P < 0.01) after the operation. The post-operative percentages of sperm DNA fragmentation in those with grades I - III VC were markedly lower (P < 0.01), but showed no significant difference from that in those with subclinical VC (P > 0.05). The percentage of big-halo sperm was significantly increased (P < 0.01), while those of the medium-, small- and non-halo sperm remarkably decreased (P < 0.01) after HLSV.</p><p><b>CONCLUSION</b>HLSV can effectively improve the sperm quality of VC patients.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Physiology
/
Sperm Count
/
Sperm Motility
/
Spermatozoa
/
General Surgery
/
Varicocele
/
Veins
/
DNA Fragmentation
/
Genetics
/
Ligation
Limits:
Adolescent
/
Adult
/
Humans
/
Male
Language:
Chinese
Journal:
National Journal of Andrology
Year:
2011
Type:
Article
Similar
MEDLINE
...
LILACS
LIS