Local injection of gentamycin for female urethral syndrome: a clinical study / 中华男科学杂志
National Journal of Andrology
;
(12): 794-798, 2011.
Article
in Chinese
| WPRIM
| ID: wpr-305788
ABSTRACT
<p><b>OBJECTIVE</b>To observe the therapeutic effect of local antibiotic injection into the female prostate on female urethral syndrome (FUS), and search for an effective treatment for this disease.</p><p><b>METHODS</b>This study included 163 FUS patients treated in the out-patient department between July 2009 and December 2010. According to the visiting order, the patients were randomly assigned to Groups A (n = 58), B (n = 55) and C (n = 50). All underwent routine treatment. Inaddition Group A received local injection of 2 ml of 80 000 U gentamycin + 2 ml of lidocaine, and Group B 2 ml of normal saline + 2 ml of lidocaine, both injected into the distal segment of the urethral back wall where the female prostate is located, twice a week for 3 weeks. The therapeutic effects were evaluated according to the changes of the patients' independent symptom scores at 2 and 4 weeks after the treatment. Disappearance of the symptoms was considered as "curative" , > 1/2 reduction in the symptom score as "obviously effective", 1/2 - > 1/4 reduction in the symptom score as "effective", and < 1/4 reduction or increase in the symptom score as "ineffective".</p><p><b>RESULTS</b>At 2 weeks after the treatment, the total effectiveness rate was significantly higher in Group A (77.5%) than in B (67.3%) and C (68.0%) (P < 0.05), but with no statistically significant difference between B and C (P > 0.05). At 4 weeks, the total effectiveness rate of Group A was slightly decreased, but still remarkably higher than that of group B or C (P < 0.05).</p><p><b>CONCLUSION</b>Local injection of gentamycin into the female prostate is effective for the treatment of female urethral syndrome.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Urethral Diseases
/
Gentamicins
/
Prospective Studies
/
Administration, Topical
/
Treatment Outcome
/
Therapeutic Uses
/
Drug Therapy
/
Injections
Type of study:
Observational study
Limits:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
Language:
Chinese
Journal:
National Journal of Andrology
Year:
2011
Type:
Article
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