Expression of Nusap1 in the surgical margins of hepatocellular carcinoma and its association with early recurrence / 南方医科大学学报
Journal of Southern Medical University
;
(12): 937-inside back cover, 2013.
Article
in Chinese
| WPRIM
| ID: wpr-306434
ABSTRACT
<p><b>OBJECTIVE</b>To detect the expression of Nusap1 of surgical margins in hepatocellular carcinoma (HCC) and investigate its association with early tumor recurrence.</p><p><b>METHODS</b>The expression of Nusap1 in the surgical margins of HCC, which were histopathologically negative for tumor cells, was examined using immunohistochemistry in 61 HCC cases.</p><p><b>RESULTS</b>Fifteen of 21 (71.4%) cases with immunohistochemical positivity for Nusap1 expression in the surgical margins had early recurrence of HCC, a rate significantly higher than that in patients with negative Nusap1 expression (12/40, 30%) (P<0.05).</p><p><b>CONCLUSIONS</b>Nusap1 expression in the surgical margins of HCC is closely correlated to early postoperative recurrence and can serve as an indicator for predicting early recurrence of HCC.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pathology
/
General Surgery
/
Immunohistochemistry
/
Carcinoma, Hepatocellular
/
Liver Neoplasms
/
Metabolism
/
Microtubule-Associated Proteins
/
Neoplasm Recurrence, Local
Limits:
Adolescent
/
Adult
/
Aged
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Journal of Southern Medical University
Year:
2013
Type:
Article
Similar
MEDLINE
...
LILACS
LIS