Experimental study on effect of erzhi tiangui recipe on quality of oocyte in mice / 中国中西医结合杂志

ABSTRACT

<p><b>OBJECTIVE</b>To observe the effect of Erzhi Tiangui recipe (ETR) on quality of oocyte in the process of external fertilization and embryo-transplantation.</p><p><b>METHODS</b>Eighty mice were randomly divided into 4 groups, Group A treated with ETR plus human menopausal gonadotropin (HMG), Group B with ETR, Group C with HMG and Group D with normal saline. Ovulation test and cleavage test were conducted to observe the effect of treatment on quality of oocytes.</p><p><b>RESULTS</b>The difference on ovulation number between Group A and C was insignificant, but the difference in comparison between the two groups was significant in aspects of oocyte morphological scoring, fertilization rate and cleavage rate (P<0.05).</p><p><b>CONCLUSION</b>ETR could play its effect synergistically with Western medicine, and raise the quality of oocytes.</p>