HIV, HCV, and HBV co-infections in a rural area of Shanxi province with a history of commercial blood donation / 生物医学与环境科学(英文)
Biomedical and Environmental Sciences
;
(12): 207-213, 2011.
Article
in English
| WPRIM
| ID: wpr-306872
ABSTRACT
<p><b>BACKGROUND</b>Unhygienic blood collection in the early 1990s led to blood-borne infections in Central China. This study aimed to estimate human immunodeficiency virus (HIV) co-infection with hepatitis C and B viruses (HCV and HBV) and their risk factors in a rural area of Shanxi Province with a history of commercial blood donation.</p><p><b>METHODS</b>A cross-sectional study was conducted in 2004. All adult residents in the target area were invited to participate in the study. Face-to-face interviews were completed and blood specimens were tested for HIV, HCV, and HBV surface antigen (HBsAg).</p><p><b>RESULTS</b>Prevalence rates of HIV, HCV, and HBsAg were 1.3% (40/3 062), 12.7% (389/3 062), and 3.5% (103/2982), respectively. Of the 40 HIV-positive specimens, 85% were HCV positive and 2.5% were HBsAg positive. The history of commercial blood donation was positively associated with HIV, HCV, and HIV/HCV co-infections, but was negatively associated with HBsAg seropositivity. Migration for employment in the last 5 years was positively related to HIV, HBsAg, and HIV/HCV co-infections. Univariate logistic analysis showed that illegal drug use, number of sex partners, extramarital sex behavior, commercial sex behavior, and condom use rate were not related to anti-HIV, anti-HCV, HBsAg seropositivity or their co-infections.</p><p><b>CONCLUSION</b>The history of commercial blood donation was the main risk factor for HIV, HCV, and HIV/HCV co-infections in this former commercial blood donation area. HIV and HCV prevention and treatment interventions are important in this area.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Blood Donors
/
HIV Infections
/
China
/
Epidemiology
/
Cross-Sectional Studies
/
Hepatitis C
/
Transfusion Reaction
/
Hepatitis B
Type of study:
Observational study
/
Prevalence study
/
Qualitative research
/
Risk factors
Limits:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
Country/Region as subject:
Asia
Language:
English
Journal:
Biomedical and Environmental Sciences
Year:
2011
Type:
Article
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