Effect of short-term intensive therapy with glimepiride and metformin in newly diagnosed type 2 diabetic patients / 南方医科大学学报
Journal of Southern Medical University
;
(12): 564-566, 2011.
Article
in Chinese
| WPRIM
| ID: wpr-307884
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the effect of short-term intensive therapy on blood glucose control, BETA-cell function, and blood lipid levels in newly diagnosed type 2 diabetic patients.</p><p><b>METHODS</b>Out-patients with newly diagnosed type 2 diabetic patients were enrolled for intensive treatment with sulfonylureas and metformin for 12 weeks, and the therapeutic effect was evaluated.</p><p><b>RESULTS</b>After the intensive treatment, FPG, 2 hPG, and HbA1c decreased significantly (P<0.01); HOMA-IR decreased and HOMA-B increased significantly (P<0.01), and TG, CHOL, LDL decreased significantly (P<0.01) after the treatment.</p><p><b>CONCLUSION</b>Short-term intensive treatment with glimepiride combined with metformin is safe and effective in newly diagnosed type 2 diabetic patients with HbA1c>9%.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Sulfonylurea Compounds
/
Treatment Outcome
/
Therapeutic Uses
/
Diabetes Mellitus, Type 2
/
Drug Therapy
/
Drug Therapy, Combination
/
Metformin
Limits:
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Journal of Southern Medical University
Year:
2011
Type:
Article
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