Therapeutic effect of pelvic methotrexate injection via the posterior fornix for treatment of tubal pregnancy / 南方医科大学学报
Journal of Southern Medical University
;
(12): 377-379, 2011.
Article
in Chinese
| WPRIM
| ID: wpr-307927
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the therapeutic effect and safety of pelvic methotrexate (MTX) injection via the posterior fornix for treatment of tubal pregnancy.</p><p><b>METHODS</b>Ninety-six patients with tubal pregnancy (mean age 21-40 years) were randomized into 3 groups for treatment with pelvic MTX injection via the posterior fornix+mifepristone+traditional Chinese medicine (experiment group), intramuscular MTX injection+mifepristone+traditional Chinese medicine (control group I), or mifepristone+traditional Chinese medicine (control group II). On days 4 and 7 of the treatment, blood β-HCG of the patients in different groups was detected, and in cases with continuous reduction of blood β-HCG or a reduction by over 15%, β-HCG was checked every week. One week after the treatment, the size of the mass was measured by B-mode ultrasound. The clearance time of β-HCG and the hospital stay of the patients were recorded.</p><p><b>RESULTS</b>Twenty-nine patients in the experimental group were treated successfully, with a cure rate of 90.6%, which was significantly higher than those in the two control groups (P<0.05). The clearance time of β-HCG and hospital stay were also much shorter in the experimental group (P<0.05).</p><p><b>CONCLUSION</b>Pelvic MTX injection via the posterior fornix is a convenient procedure associated with minimal complications and serves as a good alternative for treatment of tubal pregnancy.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pelvis
/
Pregnancy, Tubal
/
Vagina
/
Drugs, Chinese Herbal
/
Abortifacient Agents, Nonsteroidal
/
Mifepristone
/
Methotrexate
/
Drug Therapy
/
Drug Therapy, Combination
/
Injections
Type of study:
Controlled clinical trial
Limits:
Adult
/
Female
/
Humans
/
Pregnancy
Language:
Chinese
Journal:
Journal of Southern Medical University
Year:
2011
Type:
Article
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