Analysis of the genetic polymorphisms of 15 autosomal short tandem repeat in a Han population of Shandong / 中华医学遗传学杂志

ABSTRACT

<p><b>OBJECTIVE</b>To obtain population genetic data at 15 short tandem repeat(STRs) in Shandong Han population.</p><p><b>METHODS</b>Fifteen STRs were genotyped in 200 unrelated individuals from Shandong Han population using Identifiler(TM) Kit.</p><p><b>RESULTS</b>In this Shandong Han population, the observed heterozygosities of the 15 loci ranged from 0.605 to 0.882, and the expected heterozygosities were 0.625-0.862, the polymorphic information contents ranged from 0.57 to 0.85, the discrimination powers ranged from 0.795 to 0.958, and the exclusion probabilities ranged from 0.297 to 0.758. The non-differentiation exact P values at TPOX loci were more than 0.05 between Shandong and Han population of Henan, Jilin, and Jiangsu. The non-differentiation exact P values between Shandong Han population and others populations were more than 0.05 at others loci. The P value at D13S317 was more than 0.05 between Shandong Han population and Ewenki population.</p><p><b>CONCLUSION</b>These loci are polymorphic in Shandong Han population, and the discrimination powers and exclusion probabilities were high in the 15 STRs except TPOX and TH01.</p>