Analysis of the relative etiology of non-obstructive azoospermia / 中华男科学杂志
National Journal of Andrology
;
(12): 616-622, 2004.
Article
in Chinese
| WPRIM
| ID: wpr-308285
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the levels and changes of sexual hormone in serum and seminal plasma, and the epidermal growth factor (EGF), alpha-glucosidase, and fructose in the seminal plasma of non-obstructive azoospermic patients, and to assess the significance of the analysis of their chromosomes.</p><p><b>METHODS</b>Thirty-six non-obstructive azoospermic males and 26 normal males were chosen. The results in reproductive endocrine and genetics obtained by radioimmunoassay, colorimetry, and chromosomes G and C banding assay were compared and analyzed to explore into the causes of infertility.</p><p><b>RESULTS</b>The levels of FSH, LH, PRL and E2 in the serum of the non-obstructive azoospermic patients were higher than those of the control group, but the T level had no significant difference between the two groups. There were no obvious differences in the sexual hormones except in FSH of the seminal plasma. There were 2 cases of abnormal sex chromosomes, 2 cases of big Y chromosomes and 7 cases of small Y chromosomes in the non-obstructive azoospermic patients. No correlation was found between EGF and fructose in the seminal plasma.</p><p><b>CONCLUSION</b>The level of sexual hormone in serum, alpha-glucosidase in seminal plasma and abnormal chromosomes might be closely related to non-obstructive azoospermia.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Semen
/
Gonadal Steroid Hormones
/
Case-Control Studies
/
Chemistry
/
Chromosome Banding
/
Chromosomes, Human, Y
/
Epidermal Growth Factor
/
Alpha-Glucosidases
/
Azoospermia
/
Genetics
Type of study:
Etiology study
/
Observational study
Limits:
Adult
/
Humans
/
Male
Language:
Chinese
Journal:
National Journal of Andrology
Year:
2004
Type:
Article
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