Chemical constituents of Coreopsis tinctoria / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 3581-3584, 2012.
Article
in Chinese
| WPRIM
| ID: wpr-308573
ABSTRACT
<p><b>OBJECTIVE</b>To study the chemical constituents of the inflorescences of Coreopsis tinctoria and provide the chemical basis for development and utilization of this plant.</p><p><b>METHOD</b>Various chromatographic techniques were employed for the isolation and purification of the constituents including silica gel, Sephadex LH-20 and pre-HPLC. The structures of compounds were elucidated by chemical and spectral analysis (NMR, IR, UV and MS).</p><p><b>RESULT</b>Eight compounds have been isolated from the inflorescences of C. tinctoria, including three organic acids which are 3,4-dihydroxybenzoicacid (1), 4-hydroxybenzoicacid (2) and caffeic acid (3), one organic ester which is 4-O-beta-D-glucopyranosyl-p-coumaric acid methyl ester (4), two flavonones which are 2S-3',5',7-trihydroxyflavanone (5) and (2R,3R)-3,4',5,7-tetrahydroxylflavanone (6), two sterols which are stigmasterol-3-O-beta-D-glucopyranoside (7) and beta-sitosterol (8).</p><p><b>CONCLUSION</b>Compounds 1-7 were isolated from genus Coreopsis for the first time and compound 8 was isolated first from C. tinctoria.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Drugs, Chinese Herbal
/
Magnetic Resonance Spectroscopy
/
Molecular Structure
/
Chemistry
/
Chromatography, High Pressure Liquid
/
Coreopsis
Language:
Chinese
Journal:
China Journal of Chinese Materia Medica
Year:
2012
Type:
Article
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