Isoflavonoids from roots of Astragalus membranaceus var. mongholicus / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 3243-3248, 2012.
Article
in Chinese
| WPRIM
| ID: wpr-308608
ABSTRACT
<p><b>OBJECTIVE</b>To study the isoflavonoid constituents of the roots of Astragalus membranaceus var. mongholicus.</p><p><b>METHOD</b>Such column chromatography methods as HPD-100 macroporous adsorption resin, silica gel, polyamide and Sephadex LH-20 gel were used for seperating and purifying isoflavonoids, and their structures were identified on the basis of spectral data.</p><p><b>RESULT</b>Fourteen compounds were separated and identified as formononetin (1), ononin (2) calycosin (3), calycosin-7-O-beta-3-D-glucopyranoside (4), (6aR, 11aR)-3-hydroxy-9,10-dimethoxypterocarpan (5), (6aR, 11aR)-3-hydroxy-9,10-dimethoxypterocarpan-3-O-beta-D-glucopyranoside (6), (3R) -7,2'-dihydroxy-3', 4'-dimethoxyisoflavan (7), (3R) -7, 2'-dihydroxy-3', 4'-dimethoxyisoflavan-7-O-beta-D-glucopyranoside (8), 6"-O-acetyl-ononin (9), 6"-O-acetyl-(3R) -7, 2'-dihydroxy-3', 4'-dimethoxyisoflavan-7-O-beta-D-glucopyranoside (10), 6"-O-acetyl-(6aR, 11aR)-3-hydroxy-9, 10-dimethoxypterocarpan-3-O-beta-D-glucopyranoside (11), pratensein (12), sissotrin (13) and 5,7,4'-trihydroxy-3'-methoxyisoflavone (14).</p><p><b>CONCLUSION</b>Compound 10 was a new compound. Compounds 9, 11, 13,14 were separated from A. membranaceus var. mongholicus for the first time.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Plant Extracts
/
Chemistry
/
Plant Roots
/
Astragalus propinquus
/
Isoflavones
Language:
Chinese
Journal:
China Journal of Chinese Materia Medica
Year:
2012
Type:
Article
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