Research progress on bisphosphonate-related osteonecrosis of the jaws / 华西口腔医学杂志
West China Journal of Stomatology
;
(6): 29-36, 2017.
Article
in Chinese
| WPRIM
| ID: wpr-309080
ABSTRACT
Bisphosphonates (BPs), as potent drugs inhibiting bone resorption, have been widely used for treatment of several diseases. In recent years, dentists and oral and maxillofacial surgeons reported continuously increasing cases of bisphosphonate-related osteonecrosis of the jaws (BRONJ). This disease is clinically characterized by exposed bones, formation of sequestrum, pain, and halitosis. Provided that pathogenesis of BRONJ is unclear, effective treatments for this disease are currently unavailable. Thus, prevention plays an important role in the management of BRONJ. This review summarizes research progress on pathogenesis, risk factors, clinical characteristics, treatment, and prevention of this condition.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Bone Resorption
/
Risk Factors
/
Treatment Outcome
/
Diphosphonates
/
Bone Density Conservation Agents
/
Bisphosphonate-Associated Osteonecrosis of the Jaw
/
Jaw
Type of study:
Etiology study
/
Risk factors
Limits:
Humans
Language:
Chinese
Journal:
West China Journal of Stomatology
Year:
2017
Type:
Article
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