Clinical study of 36 cases with adenoid cystic carcinoma of the maxillary sinus / 中华耳鼻咽喉头颈外科杂志
Chinese Journal of Otorhinolaryngology Head and Neck Surgery
;
(12): 37-40, 2008.
Article
in Chinese
| WPRIM
| ID: wpr-309364
ABSTRACT
<p><b>OBJECTIVE</b>To study the clinical characters, management and the prognosis of patients with adenoid cystic carcinoma of the maxillary sinus.</p><p><b>METHODS</b>The clinical data were analyzed retrospectively for 36 patients with adenoid cystic carcinoma of the maxillary sinus to evaluate the treatment results of different modalities. The contribution of every factors influencing on survival were also analyzed. Survival analysis was performed by life table method, comparison among/between groups was performed using log-rank test, and multivariate analysis was carried out using Cox proportional hazard model.</p><p><b>RESULTS</b>The 5-year survival rate was 58.33% in all patients, while they were only 75.0% and 42.9% in stage III and stage IV lesions respectively. The 5-year survival rate of 66.7% was obtained in patients who received surgery combined with radiotherapy,71.4% and 12.5% respectively in those treated by surgery and by radiotherapy alone. Multivariate analysis indicated that stage, treatment modality, and the tumour residues in the primary treatment were the predict factors for the prognosis.</p><p><b>CONCLUSIONS</b>Advanced adenoid cystic carcinoma should be treated by combined surgery and radiotherapy. Stage, treatment approach and short-term therapeutic response are the most important factors affecting the prognosis of the patients with adenoid cystic carcinoma of the maxillary sinus.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Prognosis
/
Therapeutics
/
Maxillary Sinus Neoplasms
/
Survival Analysis
/
Survival Rate
/
Retrospective Studies
/
Mortality
/
Carcinoma, Adenoid Cystic
/
Diagnosis
/
Neoplasm Staging
Type of study:
Diagnostic study
/
Observational study
/
Prognostic study
Limits:
Adolescent
/
Adult
/
Aged
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Chinese Journal of Otorhinolaryngology Head and Neck Surgery
Year:
2008
Type:
Article
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