Preliminary study on immunosuppressive effects evaluation of biomaterial / 中国医疗器械杂志
Chinese Journal of Medical Instrumentation
;
(6): 20-22, 2009.
Article
in Chinese
| WPRIM
| ID: wpr-309544
ABSTRACT
In this paper, an immunosuppression model of immunotoxicity built through applying immunosuppressive agent-cyclophosphamide. Subsequently the changes of some assessment indexes including total amount of lymphocytes and concentration of cytokine TNF-alpha in peripheral blood were observed and were used to evaluate immunotoxicity induced by Medical Heat Vulcanizing Silicone Rubber. The final results showed no immunosuppressive effect caused by this material. The study provide effective and sensitive detection technique for evaluation of medical devices and biomaterials' immunotoxicity.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Rubber
/
Silicones
/
Biocompatible Materials
/
Blood
/
Materials Testing
/
Lymphocytes
/
Tumor Necrosis Factor-alpha
/
Elastomers
/
Allergy and Immunology
/
Toxicity
Type of study:
Prognostic study
Limits:
Animals
Language:
Chinese
Journal:
Chinese Journal of Medical Instrumentation
Year:
2009
Type:
Article
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