Correlation between di-2-ethylhexyl phthalate and idiopathic oligoasthenospermia / 中华男科学杂志
National Journal of Andrology
;
(12): 702-705, 2014.
Article
in Chinese
| WPRIM
| ID: wpr-309653
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the relationship between the level of di-2-ethylhexyl phthalate (DEHP) and idiopathic oligoasthenospermia by measuring the content of DEHP in the semen samples of different subjects.</p><p><b>METHODS</b>We obtained semen samples from 100 infertile men with idiopathic oligoasthenospermia, 50 working all the year round in the plastic greenhouse (group A) and the other 50 constantly dining from plastic meal boxes (group B). We also enrolled 50 normal male volunteers as controls (group C). We conducted semen analyses using a computer-assisted sperm analyzer, measured the DEHP concentration by reversed-phase high-pressure liquid chromatography, and subjected the data to statistic processing by t-test and correlation analysis.</p><p><b>RESULTS</b>The mean concentrations of DEHP in the seminal plasma were (0.72 +/- 0.48), (0.71 +/- 0.49) and (0.21 +/- 0.18) mg/L in groups A, B and C, respectively, significantly higher in A and B than in C (both P < 0.05). The DEHP concentration was negatively correlated with sperm motility (P < 0.05).</p><p><b>CONCLUSION</b>The DEHP level in the seminal plasma is higher in infertile men frequently exposed to plastic products than in normal males and excessive DEHP may be one of the important factors of idiopathic male infertility.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Oligospermia
/
Plastics
/
Semen
/
Case-Control Studies
/
Chemistry
/
Diethylhexyl Phthalate
Type of study:
Observational study
Limits:
Adult
/
Humans
/
Male
Language:
Chinese
Journal:
National Journal of Andrology
Year:
2014
Type:
Article
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