Primary testicular yolk sac tumor: clinicopathological study of 8 cases / 中华男科学杂志
National Journal of Andrology
;
(12): 435-438, 2014.
Article
in Chinese
| WPRIM
| ID: wpr-309693
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the clinicopathological characteristics, diagnosis and treatment of primary testicular yolk sac tumor (YST).</p><p><b>METHODS</b>We studied 8 cases of primary testicular YST by microscopy and immunohistochemistry.</p><p><b>RESULTS</b>The 8 cases of primary testicular YST, including 2 consultation cases, were confirmed from 1998 to 2013, accounting for 10.7% (8/75) of all the testicular germ cell tumors diagnosed in our hospital. The patients ranged in age from 7 to 43 years, 23.9 years on average. The main clinical manifestation of the patients was painless unilateral testis swelling. Microscopically, reticular tissues, schiller-duvaI (S-D) bodies, and eosin-stain transparent bodies were seen in the tumors. One of the cases was confirmed to be simple YST, while the other 7 mixed YST. AFP was a characteristic immunophenotype marker of the tumors.</p><p><b>CONCLUSION</b>Primary testicular YST is a rare malignancyr with poor prognosis. Its diagnosis depends on preoperative AFP test and postoperative pathology. Comprehensive treatment, including orchiectomy, chemotherapy, and radiotherapy, can prolong the survival of the patients.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pathology
/
Testicular Neoplasms
/
Therapeutics
/
Immunohistochemistry
/
Orchiectomy
/
Endodermal Sinus Tumor
/
Neoplasms, Germ Cell and Embryonal
/
Rare Diseases
/
Metabolism
Type of study:
Prognostic study
Limits:
Adolescent
/
Adult
/
Child
/
Humans
/
Male
Language:
Chinese
Journal:
National Journal of Andrology
Year:
2014
Type:
Article
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