Cyclooxygenase-2 and cyclooxygenase-2 inhibitors in prostate cancer / 中华男科学杂志
National Journal of Andrology
;
(12): 1031-1034, 2008.
Article
in Chinese
| WPRIM
| ID: wpr-309763
ABSTRACT
Cyclooxygenase-2 (Cox-2) is over-expressed in prostate cancer (PCa) and involved in its development and progression by facilitating inflammatory response, reducing cell apoptosis, increasing angiogenesis and damaging DNA oxidation. Selective Cox-2 inhibitors suppress PCa growth through various channels and therefore have a promising application value in the management of prostate cancer.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Prostatic Neoplasms
/
Apoptosis
/
Therapeutic Uses
/
Drug Therapy
/
Cyclooxygenase 2
/
Cyclooxygenase 2 Inhibitors
/
Metabolism
Limits:
Humans
/
Male
Language:
Chinese
Journal:
National Journal of Andrology
Year:
2008
Type:
Article
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