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Cyclooxygenase-2 and cyclooxygenase-2 inhibitors in prostate cancer / 中华男科学杂志
National Journal of Andrology ; (12): 1031-1034, 2008.
Article in Chinese | WPRIM | ID: wpr-309763
ABSTRACT
Cyclooxygenase-2 (Cox-2) is over-expressed in prostate cancer (PCa) and involved in its development and progression by facilitating inflammatory response, reducing cell apoptosis, increasing angiogenesis and damaging DNA oxidation. Selective Cox-2 inhibitors suppress PCa growth through various channels and therefore have a promising application value in the management of prostate cancer.
Subject(s)
Full text: Available Index: WPRIM (Western Pacific) Main subject: Prostatic Neoplasms / Apoptosis / Therapeutic Uses / Drug Therapy / Cyclooxygenase 2 / Cyclooxygenase 2 Inhibitors / Metabolism Limits: Humans / Male Language: Chinese Journal: National Journal of Andrology Year: 2008 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Prostatic Neoplasms / Apoptosis / Therapeutic Uses / Drug Therapy / Cyclooxygenase 2 / Cyclooxygenase 2 Inhibitors / Metabolism Limits: Humans / Male Language: Chinese Journal: National Journal of Andrology Year: 2008 Type: Article