Electrospinning and morphology of ultrafine poly (D, L-lactide) fibers / 生物医学工程学杂志
Journal of Biomedical Engineering
;
(6): 1245-1248, 2005.
Article
in Chinese
| WPRIM
| ID: wpr-309910
ABSTRACT
Ultrafine poly (D, L-lactide) (PLA) fibers with diameter less than 200 nm produced by electrospinning were studied to obtain tissue restoration resembling extracellular matrix. Scanning electron microscopy was used to observe the fiber morphology. Results showed that the solvent was the critical factor to determine the formation of the electrospun PLA fibers. Compared with acetone, N,N-dimethylformamide (DMF) was a better solvent for PLA to electrospin. Entrance of an organic salt, triethylbenzylammonium chlorate, led to a great increase of the conductivity of PLA/DMF solutions, so that the average fiber diameter of the electrospun PLA fibers decreased dramatically from 500 nm to 100-200 nm. The addition of surfactant, Span-80, did not improve the fiber morphology but formed beaded fiber web.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Polyesters
/
Surface Tension
/
Biocompatible Materials
/
Microscopy, Electron, Scanning
/
Chemistry
/
Dimethylformamide
/
Electricity
/
Electrochemistry
/
Fiber Optic Technology
/
Methods
Language:
Chinese
Journal:
Journal of Biomedical Engineering
Year:
2005
Type:
Article
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