Function of TM4SF-integrins complexes in regulating cancer metastasis

Lin-jing ZHU; Chong LAI

Function of TM4SF-integrins complexes in regulating cancer metastasis / 浙江大学学报·医学版

Lin-jing ZHU; Chong LAI.

Journal of Zhejiang University. Medical sciences ; (6): 208-214, 2009.

Article in Chinese | WPRIM | ID: wpr-310365

ABSTRACT

ABSTRACT

Distant metastasis is the main cause of cancer death. Tetraspanins (transmembrane 4 superfamily, TM4SF) is capable of forming transmembrane complexes with integrin family participating in cell adhesion, migration and tumor metastasis. This review elucidates the structure of tetraspanins and its function in regulating metastasis as form of multimolecular transmembrane complexes with integrin.

Subject(s)

Humans; Cell Adhesion; Integrins; Chemistry; Metabolism; Physiology; Membrane Proteins; Chemistry; Metabolism; Physiology; Neoplasm Metastasis; Neoplasms; Metabolism; Pathology; Tetraspanins

Fulltext

XML

Search on Google

Full text: Available Index: WPRIM (Western Pacific) Main subject: Pathology / Physiology / Integrins / Cell Adhesion / Chemistry / Tetraspanins / Membrane Proteins / Metabolism / Neoplasm Metastasis / Neoplasms Limits: Humans Language: Chinese Journal: Journal of Zhejiang University. Medical sciences Year: 2009 Type: Article

Similar

MEDLINE

LILACS

LIS

Fulltext

XML

Search on Google