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Relationship between alcohol consumption and risk factors for cardiovascular disease / 浙江大学学报·医学版
Article in Chinese | WPRIM | ID: wpr-310386
Responsible library: WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the relationship between alcohol consumption and risk factors for cardiovascular disease.</p><p><b>METHODS</b>Two hundreds and twenty six subjects were enrolled in the study and grouped to non-drinkers, mild drinkers, moderate drinkers and heavy drinkers. Serum GGT, hs-CRP, %CDT, HCY, lipoprotein were measured in all groups.</p><p><b>RESULT</b>There were significantly higher GGT levels with heavy drinkers than those with other groups (P <0.05), and GGT levels were increased with increasing alcohol intake; and there were significantly higher %CDT levels with heavy drinkers compared with those with no-drinkers; there was significant higher hs-CRP levels with heavy drinkers compared with those with mild and moderate drinkers (P<0.05); but in moderate drinkers there was significantly lower hs-CRP levels than non drinkers (P<0.05). Compared with non-drinkers, there were significantly lower LDL-C and TG levels with mild and moderate drinkers. There were no significant differences in CHOL, HDL-C, HCY, WBC, MCV levels among all groups. Heavy drinkers had higher smoking rate and higher prevalence of hypertension (P <0.05).</p><p><b>CONCLUSION</b>Heavy alcohol consumption results in increasing GGT,%CDT and hs-CRP and may increase cardiovascular disease risk along with other risk factors.Mild to moderate alcohol consumption is associated with lower hs-CRP concentration,which may protect the cardiovascular system through anti-inflammatory mechanism.</p>
Subject(s)
Full text: Available Index: WPRIM (Western Pacific) Main subject: Blood / Aged / Humans / Male / Alcohol Drinking / C-Reactive Protein / Transferrin / Cardiovascular Diseases / China / Epidemiology Country/Region as subject: Asia Language: Chinese Journal: Journal of Zhejiang University. Medical sciences Year: 2009 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Blood / Aged / Humans / Male / Alcohol Drinking / C-Reactive Protein / Transferrin / Cardiovascular Diseases / China / Epidemiology Country/Region as subject: Asia Language: Chinese Journal: Journal of Zhejiang University. Medical sciences Year: 2009 Type: Article