Relationship between alcohol consumption and risk factors for cardiovascular disease / 浙江大学学报·医学版
Journal of Zhejiang University. Medical sciences
;
(6): 89-94, 2009.
Article
in Chinese
| WPRIM
| ID: wpr-310386
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the relationship between alcohol consumption and risk factors for cardiovascular disease.</p><p><b>METHODS</b>Two hundreds and twenty six subjects were enrolled in the study and grouped to non-drinkers, mild drinkers, moderate drinkers and heavy drinkers. Serum GGT, hs-CRP, %CDT, HCY, lipoprotein were measured in all groups.</p><p><b>RESULT</b>There were significantly higher GGT levels with heavy drinkers than those with other groups (P <0.05), and GGT levels were increased with increasing alcohol intake; and there were significantly higher %CDT levels with heavy drinkers compared with those with no-drinkers; there was significant higher hs-CRP levels with heavy drinkers compared with those with mild and moderate drinkers (P<0.05); but in moderate drinkers there was significantly lower hs-CRP levels than non drinkers (P<0.05). Compared with non-drinkers, there were significantly lower LDL-C and TG levels with mild and moderate drinkers. There were no significant differences in CHOL, HDL-C, HCY, WBC, MCV levels among all groups. Heavy drinkers had higher smoking rate and higher prevalence of hypertension (P <0.05).</p><p><b>CONCLUSION</b>Heavy alcohol consumption results in increasing GGT,%CDT and hs-CRP and may increase cardiovascular disease risk along with other risk factors.Mild to moderate alcohol consumption is associated with lower hs-CRP concentration,which may protect the cardiovascular system through anti-inflammatory mechanism.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Blood
/
Alcohol Drinking
/
C-Reactive Protein
/
Transferrin
/
Cardiovascular Diseases
/
China
/
Epidemiology
/
Surveys and Questionnaires
/
Risk Factors
/
Alcoholism
Type of study:
Etiology study
/
Risk factors
Limits:
Adolescent
/
Adult
/
Aged
/
Humans
/
Male
Country/Region as subject:
Asia
Language:
Chinese
Journal:
Journal of Zhejiang University. Medical sciences
Year:
2009
Type:
Article
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