Your browser doesn't support javascript.
loading
Effects of gypsum on the firing of pyrogen-treated thermosensitive neurons in PO/AH of cats / 中国应用生理学杂志
Chinese Journal of Applied Physiology ; (6): 320-323, 2008.
Article in Chinese | WPRIM | ID: wpr-310735
ABSTRACT
<p><b>AIM</b>To investigate the possible central mechanism of antipyretic effects of Chinese medicine gypsum.</p><p><b>METHODS</b>Gypsum was injected after the fever model was established. The firing rate of thermosensitive neurons in preoptic-anterior hypothalamus(PO/AH) region was recorded by using extracellular microelectrode technique.</p><p><b>RESULTS</b>The injection of pyrogen evoked decrease in firing rate of the warm-sensitive neurons and increase in the cold-sensitive neurons in the region of PO/AH; the changes of the firing rate of pyrogen- treated warm-sensitive and cold-sensitive neurons could be reversed by the injection of gypsum.</p><p><b>CONCLUSION</b>The result may suggest that antipyretic action of gypsum is mediated by its influences on the thermosensitivity neurons in the region of PO/AH.</p>
Subject(s)
Full text: Available Index: WPRIM (Western Pacific) Main subject: Pharmacology / Physiology / Preoptic Area / Pyrogens / Action Potentials / Calcium Sulfate / Hypothalamus, Anterior / Materia Medica / Antipyretics / Fever Limits: Animals Language: Chinese Journal: Chinese Journal of Applied Physiology Year: 2008 Type: Article

Similar

MEDLINE

...
LILACS

LIS

Full text: Available Index: WPRIM (Western Pacific) Main subject: Pharmacology / Physiology / Preoptic Area / Pyrogens / Action Potentials / Calcium Sulfate / Hypothalamus, Anterior / Materia Medica / Antipyretics / Fever Limits: Animals Language: Chinese Journal: Chinese Journal of Applied Physiology Year: 2008 Type: Article