The expressional alterations of CSF-1R after ischemic injury of cerebral cortex / 中国应用生理学杂志
Chinese Journal of Applied Physiology
;
(6): 6-9, 2008.
Article
in Chinese
| WPRIM
| ID: wpr-310819
ABSTRACT
<p><b>AIM</b>To observe the expressional alterations of colony stimulating factor-1 receptor (CSF-1R) after ischemic injury of cerebral cortex, and study the function of colony stimulating factor-1 (CSF-1)/CSF-1R signal during the process of ischemic injury and repair of central nervous system (CNS).</p><p><b>METHODS</b>We examined the distribution and expression of CSF-1R in normal brain tissues and ischemic brain tissues by immunohistology and Western blot analysis.</p><p><b>RESULTS</b>The expression of CSF-1R in neurons could be up-regulated by ischemic injury in CNS.</p><p><b>CONCLUSION</b>CSF-1/CSF-1R might take part in the process of ischemic injury and repair.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pathology
/
Physiology
/
Reperfusion Injury
/
Random Allocation
/
Cerebral Cortex
/
Brain Ischemia
/
Macrophage Colony-Stimulating Factor
/
Receptor, Macrophage Colony-Stimulating Factor
/
Genetics
/
Metabolism
Limits:
Animals
Language:
Chinese
Journal:
Chinese Journal of Applied Physiology
Year:
2008
Type:
Article
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