Comparative study on image analysis and manual counting of immunohistochemistry / 生物医学工程学杂志
Journal of Biomedical Engineering
;
(6): 288-290, 2003.
Article
in Chinese
| WPRIM
| ID: wpr-311053
ABSTRACT
With the use of computer image analysis (IA) and manual counting, the immunohistochemistry (IHC) results on PS2, ER and c-erB-2 of breast cancer which represent positive expression of cytoplasm, cell nucleus and cytomembrane are analyzed and compared. Then the advantages, disadvantages and repetition of the two methods are discussed and the correlation between image analysis and manual counting is estimated. The results of this study indicate that IA has better repetition in estimation of positive expression of cytoplasm, cell nucleus and cytomembrane, whereas manual counting has better repetition only in the positive expression of cell nucleus and cytomembrane, and the two methods have positive correlation in estimation of IHC results. In addition, some problems in image processing are discussed in this paper.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pathology
/
Image Processing, Computer-Assisted
/
Breast Neoplasms
/
Immunohistochemistry
/
Receptors, Progesterone
/
Receptors, Estrogen
/
Cluster Analysis
/
Cell Count
/
Receptor, ErbB-2
/
Methods
Limits:
Female
/
Humans
Language:
Chinese
Journal:
Journal of Biomedical Engineering
Year:
2003
Type:
Article
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