Investigation of the degradation behavior of different modified bovine pericardial in vitro / 生物医学工程学杂志
Journal of Biomedical Engineering
;
(6): 214-218, 2003.
Article
in Chinese
| WPRIM
| ID: wpr-311071
ABSTRACT
Bovine pericardium is mainly composed of collagen which has many good properties of extracellular matrix. This in vitro study was performed to quantitatively investigate and compare the degradation behavior of the bovine pericardial, which were modified with different methods. The purpose is to find out one method that presents not only the degradation regularity of material but also minimum antigenicity, so that bovine pericardium can be used as a well degradable guide tissue regeneration material. The results of the experiments showed that the bovine pericardium treated with ethanol is more appreciated than that treated with epoxy cross-linking agent or glutaraldehyde. The mensuration of protein and special amino acid may be a useful base of constructing a mathematic model for further researches on the rate of degradation of bovine pericardium.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pericardium
/
Pharmacology
/
Prosthesis Design
/
Surface Properties
/
Biodegradation, Environmental
/
Bioprosthesis
/
In Vitro Techniques
/
Materials Testing
/
Proteins
/
Chemistry
Limits:
Animals
Language:
Chinese
Journal:
Journal of Biomedical Engineering
Year:
2003
Type:
Article
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