The roles of VEGF and C-myc in occurrence, development and metastasis of gallbladder carcinoma / 生物医学工程学杂志
Journal of Biomedical Engineering
; (6): 68-70, 2003.
Article
in Zh
| WPRIM
| ID: wpr-311106
Responsible library:
WPRO
ABSTRACT
To investigate the relationship of the expression of vascular endothelial growth factor (VEGF) and C-myc with the occurrence, development and metastasis of gallbladder carcinoma, the expression levels of VEGF and C-myc in gallbladder carcinoma tissue (n = 30) and in normal gallbladder tissue (n = 20) were examined by immunochemistry. Results show that the positive rates of VEGF and C-myc in gallbladder carcinoma tissue were 80% and 63.3% respectively, and 45% and 25% respectively in normal gallbladder tissue. The positive rates of VEGF and C-myc were significantly higher in gallbladder carcinoma than in normal gallbladder tissue. The expression of VEGF and C-myc in gallbladder carcinoma related to the metastasis of gallbladder carcinoma. VEGF and C-myc play important roles in the occurrence, development and metastasis of gallbladder carcinoma.
Full text:
1
Index:
WPRIM
Main subject:
Pathology
/
Physiology
/
Endothelial Growth Factors
/
Proto-Oncogene Proteins c-myc
/
Lymphokines
/
Intercellular Signaling Peptides and Proteins
/
Vascular Endothelial Growth Factors
/
Vascular Endothelial Growth Factor A
/
Gallbladder Neoplasms
/
Metabolism
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
Language:
Zh
Journal:
Journal of Biomedical Engineering
Year:
2003
Type:
Article