Candida infection in patients with acute necrotizing pancreatitis / 中华外科杂志
Chinese Journal of Surgery
;
(12): 726-728, 2003.
Article
in Chinese
| WPRIM
| ID: wpr-311171
ABSTRACT
<p><b>OBJECTIVE</b>To summarize our hospital's experience in the diagnosis and treatment of Candida infection in patients with acute necrotizing pancreatitis (ANP).</p><p><b>METHODS</b>Seventy-eight cases with ANP were reviewed. There were diagnoses either by operative finding or by CT scanning. Sixty-two cases received prophylactic antibiotic treatment, other sixteen did not. For cultivation of Candida, blood, urine, stool, sputum and wound drainage fluid culture, and swabs were examined microbiologically for fungi.</p><p><b>RESULTS</b>The incidence of Candida infection in all patients with ANP was 17.9% (14/78) and mortality was 28.6% (4/14). The incidence of prophylactic antibiotic group was 19.4% (12/62) and mortality was 25.0% (3/12). Non prophylactic group was 12.5% (2/16) and 50.0%.</p><p><b>CONCLUSIONS</b>Our data provide evidence for the clinical significance of Candida infection in patients with ANP. The current prophylactic antibiotic treatment can prevent a septic course of the ANP, but might lead to the evolution of Candida infection.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Candidiasis
/
Pancreatitis, Acute Necrotizing
/
Drug Therapy
Limits:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Chinese Journal of Surgery
Year:
2003
Type:
Article
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