Experimental study of diode-laser induced thermocoagulation on hepatic tissue with scanner fiber tip / 中华外科杂志
Chinese Journal of Surgery
;
(12): 849-851, 2003.
Article
in Chinese
| WPRIM
| ID: wpr-311192
ABSTRACT
<p><b>OBJECTIVE</b>To seek a safe, efficient, and cost-effective technique for local thermo-ablation of hepatic cancer.</p><p><b>METHODS</b>The livers from 16 healthy rabbits were thermocoagulated by diode-laser with scanner fiber tip, 6 w for 10 mins. At the same time, the temperatures were measured at 0, 5 and 10 mm from laser tip. The pre-thermocoagulative liver function was compared with that of 7 days post-thermocoagulation. The pathologic changes were also observed 1 month after laser thermocoagulation.</p><p><b>RESULTS</b>All the rabbits survived and hepatic tissue temperatures at 0, 5, 10 mm from laser tip reached 96.39 degrees C +/- 3.97 degrees C, 60.79 degrees C +/- 6.21 degrees C, 46.10 degrees C +/- 4.58 degrees C respectively after 10 minutes of thermocoagulation. There were no significant differences in liver function parameters between rabbits of pre-laser thermocoagulation and of post-laser thermocoagulation. Thermocoagulated necrosis of liver tissue with surrounding fibrosis in a diameter of 26.0 mm was formed. Light microscopy revealed coagulative necrosis in the center of the coagulated area without surviving hepatic cells.</p><p><b>CONCLUSION</b>The hepatic tissue can be coagulated safely and effectively by diode-laser with scanner fibertip, and such a technique may provide a new method for the treatment of hepatic carcinoma.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pathology
/
General Surgery
/
Laser Coagulation
/
Liver Neoplasms
/
Methods
Limits:
Animals
Language:
Chinese
Journal:
Chinese Journal of Surgery
Year:
2003
Type:
Article
Similar
MEDLINE
...
LILACS
LIS