Intestinal Microbial Community Differs between Acute Pancreatitis Patients and Healthy Volunteers / 生物医学与环境科学(英文)
Biomedical and Environmental Sciences
;
(12): 81-86, 2018.
Article
in English
| WPRIM
| ID: wpr-311316
ABSTRACT
A case control study including 45 acute pancreatitis and 44 healthy volunteers was performed to investigate the association between intestinal microbial community and acute pancreatitis. High-throughput 16S rRNA gene amplicon sequencing was used to profile the microbiological composition of the samples. In total, 27 microbial phyla were detected and the samples of pancreatitis patients contained fewer phyla. Samples from acute pancreatitis patients contained more Bacteroidetes and Proteobacteria and fewer Firmicutes and Actinobacteria than those from healthy volunteers. PCoA analyses distinguished the fecal microbial communities of acute pancreatitis patients from those of healthy volunteers. The intestinal microbes of acute pancreatitis patients are different from those of healthy volunteers. Modulation of the intestinal microbiome may serve as an alternative strategy for treating acute pancreatitis.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Observational study
/
Risk factors
Language:
English
Journal:
Biomedical and Environmental Sciences
Year:
2018
Type:
Article
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