Disorders of Ribosomal Proteins and Related Hematologic Diseases -Review / 中国实验血液学杂志
Journal of Experimental Hematology
;
(6): 1892-1896, 2016.
Article
in Chinese
| WPRIM
| ID: wpr-311607
ABSTRACT
Ribosomal proteins are key elements of protein synthesis machinery, ribosome. Besides the essential role in ribosome assembly and protein synthesis, there are lots of extraribosomal functions for ribosomal proteins, ranging from regulating cell proliferation and apoptosis to mediating DNA repair, cellular development and differentiation. Based on the typical features of hematologic system, the ribosomal proteins are related with many hematologic diseases, such as Diamond-Blackfan anemia, 5q- syndrome. In this review, the recent research progress on extraribosomal functions and related hematologic diseases are summarised.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Experimental Hematology
Year:
2016
Type:
Article
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