Human umbilical cord mesenchymal stem cells and the treatment of spinal cord injury / 中华医学杂志(英文版)
Chinese Medical Journal
;
(24): 225-231, 2009.
Article
in English
| WPRIM
| ID: wpr-311887
ABSTRACT
<p><b>OBJECTIVE</b>To review the recent studies about human umbilical cord mesenchymal stem cells (hUCMSCs) and advances in the treatment of spinal cord injury. Data sources Published articles (1983 - 2007) about hUCMSCs and spinal cord injury were selected using Medline. Study selection Articles selected were relevant to development of mesenchymal stem cells (MSCs) for transplantation in spinal cord injury therapy. Of 258 originally identified articles 51 were selected that specifically addressed the stated purpose.</p><p><b>RESULTS</b>Recent work has revealed that hUCMSCs share most of the characteristics with MSCs derived from bone marrow and are more appropriate to transplantation for cell based therapies.</p><p><b>CONCLUSIONS</b>Human umbilical cord could be regarded as a source of MSCs for experimental and clinical needs. In addition, as a peculiar source of stem cells, hUCMSCs may play an important role in the treatment of spinal cord injury.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pathology
/
Physiology
/
Spinal Cord Injuries
/
Therapeutics
/
Umbilical Cord
/
Cell Biology
/
Stem Cell Transplantation
/
Mesenchymal Stem Cells
/
Models, Biological
Type of study:
Prognostic study
Limits:
Humans
Language:
English
Journal:
Chinese Medical Journal
Year:
2009
Type:
Article
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