Relationship between fetal growth restriction and ovarian reserve in adulthood / 南方医科大学学报

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the relationship between fetal growth restriction and decreased ovarian reserve (DOR) in adulthood to screen high-risk population for early interventions.</p><p><b>METHODS</b>Forty-four patients with FGR and 88 normal women aged 18-40 years were enrolled. All the subjects were examined for serum levels of follicle-stimulating hormone (FSH), inhibin B (INH-B), and anti-mullerian hormone (AMH) using enzyme-linked immunosorbent assay method in the first 3-5 days of the menstrual cycle, and the counts of antrum ovarian follicle were detected by transvaginal or transabdominal ultrasonography.</p><p><b>RESULTS</b>The serum levels FSH, INHB, AMH, and AFC in FGR group differed significantly from those in the control group (P<0.05).</p><p><b>CONCLUSION</b>FGR will affect reproductive endocrine function in adulthood to cause a decreased ovarian reserve.</p>