Result of Radiotherapy in Non-metastatic Esophageal Cancer / 대한치료방사선과학회지

ABSTRACT

PURPOSE: This study was done to evaluate preliminarly the role of intraluminal brachytherapy in the radiation treatment of non-metastatic esophageal cancer. MATERIALS AND METHODS: We analyzed follow-up result of 21 patients treated at the dept. of therapeutic radiology in Gyeongsang national university hospital between April, 1989 and August, 1992. All patients received neoadjuvant chemotherapy(5-FU, Cispl-atin). Fifteen patients were treated with eternal beam alone, and in remaining 6 patients, the external beam radiotherapy followed by intraluminal brachytherapy was done. RESULTS: Among 21 patients, 7 patients showed complete tumor regression after completion of radiotherapy. But 2 of these complete responder recurred at at the site of primary disease, so ultimate local control rate was 23.8%(5/21). Local control rate according to radiation treatment modality was 6.7%(1/15) in patients treated with external irradiation only, and 66.7% in patients treated with combined external irradiation and intraluminal brachytherapy. The 2 year NED survival rate was 6.6% in the former and 66.7% in the latter. CONCLUSION: Although there should be consideration about case selection for addition of intraluminal brachytherapy, intraluminal brachytherapy may be considered as one of the method to enhance the local control probability of esophageal cancer