IgE level of cord blood in neonates with meconium-stained amniotic fluid / 中国当代儿科杂志
Chinese Journal of Contemporary Pediatrics
;
(12): 361-363, 2007.
Article
in Chinese
| WPRIM
| ID: wpr-312697
ABSTRACT
<p><b>OBJECTIVE</b>To study the effects of meconium-stained amniotic fluid on the cord blood IgE level in neonates.</p><p><b>METHODS</b>A total of 404 neonates with meconium-stained amniotic fluid who were born by cesarean delivery between August 2003 and August 2005 (meconium-stained group) and 256 neonates with normal amniotic fluid delivered by cesarean (control group) were enrolled in this study. The meconium-stained group consisted of 80 cases of mild, 62 cases of moderate and 262 cases of severe meconium-stained amniotic fluid. The cord blood IgE level was measured using ELISA.</p><p><b>RESULTS</b>The cord blood IgE level in the meconium-stained group was statistically higher than that in the control group (t = 4.03, P < 0.01). There were significant differences between the mild and severe meconium-stained subgroups and the control group for the cord blood IgE level (F=4.28, P < 0.01). The cord blood IgE level in neonates with premature rupture of the membrane between the meconium-stained and the control groups was statistically different. Sexes, gestational age, birth weight and birth order were not associated with the IgE level of cord blood.</p><p><b>CONCLUSIONS</b>The cord blood IgE levels in neonates with meconium-stained amniotic fluid increase. Premature rupture of the membranes may be associated with an increase of cord blood IgE level.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Asthma
/
Blood
/
Immunoglobulin E
/
Meconium Aspiration Syndrome
/
Chemistry
/
Allergy and Immunology
/
Fetal Blood
/
Amniotic Fluid
/
Meconium
Limits:
Humans
/
Infant, Newborn
Language:
Chinese
Journal:
Chinese Journal of Contemporary Pediatrics
Year:
2007
Type:
Article
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