Different courses of esomeprazole-based triple therapy for Helicobactor pylori infection in children / 中国当代儿科杂志
Chinese Journal of Contemporary Pediatrics
;
(12): 205-206, 2007.
Article
in Chinese
| WPRIM
| ID: wpr-312740
ABSTRACT
<p><b>OBJECTIVE</b>To study the efficacy of esomeprazole-based 1 week or 2 weeks triple therapy for Helicobactor pylori (H. pylori) infection in children.</p><p><b>METHODS</b>One hundred and five children with H. pylori infection identified by 13C-UBT were randomly assigned into Group A (n=60) and Group B (n=45). The patients of the two groups were administered with 1 week or 2 weeks triple therapy consisting of esomeprazole, clarithromycin and amoxillin, respectively. They were followed up four weeks after drug withdrawal.</p><p><b>RESULTS</b>Recurrent abdominal pain was relieved in all of patients. Fifty-five patients (91.7%) showed 13C-UBT negative in Group A and 42 (93.3%) presented negative in Group B. There was no significant difference in the eradication rate of H. pylori.</p><p><b>CONCLUSIONS</b>Esomeprazole-based triple therapy for H. pylori infection is effective in children. The efficacy of esomeprazole-based 1 week or 2 weeks triple therapy for this disorder does not appear to be different.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Helicobacter pylori
/
Helicobacter Infections
/
Clarithromycin
/
Drug Therapy
/
Drug Therapy, Combination
/
Esomeprazole
/
Amoxicillin
/
Anti-Ulcer Agents
/
Anti-Bacterial Agents
Limits:
Adolescent
/
Child
/
Child, preschool
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Chinese Journal of Contemporary Pediatrics
Year:
2007
Type:
Article
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