A model study on noninvasive blood glucose measurement with multi-wavelength infrared array / 生物医学工程学杂志

ABSTRACT

The concentration of glucose in the blood may soon be measured noninvasively by near infrared multi-wavelength sensor array without the painful puncture for obtaining a drop of blood. For overcoming the limitation of low measuring accurate degree and unstable working state, according to the Lambert-Beer Law, the authors analyzed the feature of blood adsorption spectroscopy and designed an infrared multi-wavelength blood glucose measuring sensor array to surmount the difficulties in noninvasive blood glucose measurement. The key technique, most suitable for detecting site and the influencing factors from human body were discussed, and the Mixture of Expert(ME) algorithm was adopted in building calibration model with multiple parameters of human body. It can overcome the existing problems and get more exact blood glucose information from the weak changes in spectral signals. Also presented and addressed in this paper are the detailed implementing steps of ME and the system, as well as the problems need to be solved.