Study of high-intensity electric pulse inhibited sarcoma for improving antitumor drug effect

Hong LI; Zishu WANG; Bisong YUE; Fangdong ZOU; Kong YANG; Jingru SUN; Baoyi WANG; Hong ZHANG; Haichuan CHEN; Guo YANG

Study of high-intensity electric pulse inhibited sarcoma for improving antitumor drug effect / 生物医学工程学杂志

Hong LI; Zishu WANG; Bisong YUE; Fangdong ZOU; Kong YANG; Jingru SUN; Baoyi WANG; Hong ZHANG; Haichuan CHEN; Guo YANG.

Journal of Biomedical Engineering ; (6): 612-614, 2003.

Article in Chinese | WPRIM | ID: wpr-312915

ABSTRACT

ABSTRACT

This article reports the experiment studies on treating the S-180 sarcomas of KM mice with high-intensity electric pulse and antitumor drug (cyclophosphamide). The results showed that the experimental group of electric field combined with drug has the best effect on tumor, compared with the control group. In addition, electric field can inhibit the formation of vas Capillaries and decrease the supply of nutrition for tumor cell. In conclusion, electric field has inhibited the growth of tumor.

Subject(s)

Animals; Mice; Antineoplastic Agents; Therapeutic Uses; Combined Modality Therapy; Cyclophosphamide; Electric Stimulation Therapy; Methods; Injections, Intralesional; Sarcoma 180; Pathology; Therapeutics; Treatment Outcome

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Pathology / Sarcoma 180 / Therapeutics / Injections, Intralesional / Electric Stimulation Therapy / Treatment Outcome / Combined Modality Therapy / Cyclophosphamide / Therapeutic Uses / Methods Limits: Animals Language: Chinese Journal: Journal of Biomedical Engineering Year: 2003 Type: Article

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