Enhancing the cytotoxicity of antitumor drugs through electromagnetic pulses / 生物医学工程学杂志
Journal of Biomedical Engineering
;
(6): 497-499, 2003.
Article
in Chinese
| WPRIM
| ID: wpr-312945
ABSTRACT
We chose Hela cells as research object and studied the cytotoxicity generated by cyclophosphamide, an antitumor drug, after cell electroporation by the use of electromagnetic pulses. Comparison between the electroporation group and the contrast group revealed the greatly enhanced cytotoxicity of the electroporation group, indicating that under some conditions electromagnetic pulses can enhance the cytotoxicity of antitumor drugs. The results of this study provide reliable evidences and a feasible approach for clinical treatment of tumor.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pharmacology
/
Drug Screening Assays, Antitumor
/
HeLa Cells
/
Cell Survival
/
Apoptosis
/
Electroporation
/
Cyclophosphamide
/
Electromagnetic Phenomena
/
Methods
/
Antineoplastic Agents
Limits:
Humans
Language:
Chinese
Journal:
Journal of Biomedical Engineering
Year:
2003
Type:
Article
Similar
MEDLINE
...
LILACS
LIS