Some clinical features on the epidemiology, clinical and microorganism of the gram-negative septicemia

ABSTRACT

146 cases of severe sepsis due to gram negative microbials in adult with average age of 54.14. The incidence of community infections(95.2% vs 4.8%). The mortality in general group is 46.6% and in shock group is 72.1%. Many criteria for determining the poor prognosis are (1) Salmonella spp, Pseudomonas spp, (2) underlying diseases such as HIV/AIDS, Cushing syndrom, (3) Complications (septic shock, acute renal failure and DIC). Effective antibiotic groups to almost Gr(-) organismes include Cephalosporin III, Oflocet, Amikacin and Netilmicin. The combination of an Aminoglycoside and a Cephalosporin III (or Oflocet or Imipenem) for empirical treatment is usually appropriate.