Research progress of tumor microenvironment and non-Hodgkin's lymphomas / 中国实验血液学杂志
Journal of Experimental Hematology
;
(6): 843-847, 2011.
Article
in Chinese
| WPRIM
| ID: wpr-313881
ABSTRACT
Non-Hodgkin's lymphoma cells including lymphoma stem cells reside in a specific microenvironment in which a series of nonmalignant bystander cells and cytokines play a crucial role in the genesis and development of non-Hodgkin's lymphomas. In addition, tumor microenvironment has important prognostic significance in Non-Hodgkin's lymphomas. Blocking the cross-talk between the tumor microenvironment and lymphoma cells may thus represent a promising new strategy for treating Non-Hodgkin's lymphomas. This review summarizes the current advance in studies of the tumor microenvironment and non-Hodgkin's lymphomas, including cells in tumor microenvironment, role of mesenchymal stem cells and stromal cells, auxiliary role of T cell subsets, macrcphage and dentritic cells, cytokines, immune surveillance and so on.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Dendritic Cells
/
Lymphoma, Non-Hodgkin
/
Cytokines
/
T-Lymphocyte Subsets
/
Allergy and Immunology
/
Tumor Microenvironment
/
Macrophages
Limits:
Humans
Language:
Chinese
Journal:
Journal of Experimental Hematology
Year:
2011
Type:
Article
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