Effect of traditional chinese medicine on survival and quality of life in patients with esophageal carcinoma after esophagectomy / 中国结合医学杂志
Chinese journal of integrative medicine
;
(12): 175-179, 2006.
Article
in English
| WPRIM
| ID: wpr-314064
ABSTRACT
<p><b>OBJECTIVE</b>To explore the effect and possible mechanism of traditional Chinese medicine (TCM) on survival and quality of life (QOL) in patients with esophageal carcinoma after esophagectomy.</p><p><b>METHODS</b>Adopting prospective controlled method of study, the authors had 128 post-esophagectomy patients, hospitalized from February 2001 to February 2002, randomly divided into 3 groups the TCM group, treated with TCM drugs alone; the chemotherapy group, with chemotherapy alone applied; and the synthetic group, treated with chemotherapy combined with Chinese medicine. Their survival rate and QOL were compared.</p><p><b>RESULTS</b>In the TCM group, the chemotherapy group and the synthetic group, the respective 3-year relapse and remote metastasis rate were 71.4%, 76.7%, 53.4%, respectively (chi(2) = 6.53, P < 0.05); the 1-year survival rate 42.9%, 46.5%, 72.1%; 2-year survival rate 28.6%, 27.9%, 55.8%, and 3-year survival rate 26.2%, 23.1%, 37.2%, respectively. And the QOL improving rate was 69.0%, 37.2%, 58.1%, respectively, all showing significant difference among them (chi(2) = 6.10, all P < 0.05). Moreover, immune function was increased in the TCM and the synthetic groups.</p><p><b>CONCLUSION</b>Integrative Chinese and Western medicinal treatment was the beneficial choice for post-operational patients with esophageal carcinoma. However, long time use of simple Chinese medicine was also advisable, especially for those in poverty.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Quality of Life
/
General Surgery
/
Blood
/
Immunoglobulins
/
Esophageal Neoplasms
/
Drugs, Chinese Herbal
/
Survival Rate
/
Prospective Studies
/
Follow-Up Studies
/
Mortality
Type of study:
Observational study
/
Prognostic study
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
Language:
English
Journal:
Chinese journal of integrative medicine
Year:
2006
Type:
Article
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