Common variable immunodeficiency: report of two cases and literature review / 中华血液学杂志
Chinese Journal of Hematology
;
(12): 111-114, 2009.
Article
in Chinese
| WPRIM
| ID: wpr-314525
ABSTRACT
<p><b>OBJECTIVE</b>To promote the awareness of common variable immunodeficiency (CVID).</p><p><b>METHODS</b>Report two cases of CVID and review related literature.</p><p><b>RESULTS</b>The two CVID patients were manifested recurrent infections of respiratory and digestive tract, splenomegaly, significantly reduced serum immunoglobulin, since adolescence. They were treated with intravenous gammaglobulin, anti-infection and symptomatic therapies and the diseases were well controlled. Case 1 was diagnosed as with spleen peripheral T cell lymphoma after splenectomy. Case 2 developed nutritional megaloblastic anemia resulting from repeated digestive tract infections.</p><p><b>CONCLUSION</b>CVID is a heterogeneous group of diseases with later-onset, characterized by hypogammaglobulinemia and recurrent bacterial infections. Early diagnosis and regular treatment may improve the prognosis.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Common Variable Immunodeficiency
/
Drug Therapy
Type of study:
Prognostic study
/
Screening study
Limits:
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Chinese Journal of Hematology
Year:
2009
Type:
Article
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